A protoculture-based reactor was required to power this type of Reflex weaponry. Reflex cannons focused their energy into beam weapons, while Reflex warheads intentionally initiate a self-destructive feedback loop, usually using a non-protoculture energy source to initiate the cycle.
The first known usage of a reflex cannon on Earth was the firing of the Super Dimension Fortress-1 Macross (SDF-1)'s gigantic main gun at the beginning of the First Robotech War in 2009. The front of the ship opened into two gigantic booms. The protoculture charge built up between these two points until enough energy was collected to fire. The range of this weapon was great enough to hit interplanetary targets and usually everything within the line of fire was vaporized. In a state of disrepair by 2014, the battle-ravaged main gun of the SDF-1 disintegrated after its final firing and was too weak to destroy just one Zentraedi vessel, its intended target.
- The name reflex was derived from a mistranslation in the scripts (provided by Tatsunoko Production) of "reaction," the shortened euphemistic term for thermonuclear reaction in The Super Dimension Fortress Macross. Coincidentally, Genesis Climber Mospeada had a location crucial to its story named Reflex Point. Macross and Mospeada were two of the three Japanese animated series which were adapted into Robotech.
- The term reaction is used in the context of power systems and warheads in the Japanese Macross series, whereas the term reflex is used in the context of energy weapons, in addition to power systems and warheads in Robotech. In Robotech, the term "reflex" refers to any major power generation system that is Protoculture based. Protoculture based powerplants are sometimes called "reflex furnaces".